Figure 4.

IE86 promotes cell proliferation and inhibits apoptosis through the hnRNP A2/B1-mediated pathway. (A) Effects of hnRNP A2/B1 knockdown on the regulation of cell proliferation in U251 cells. Cells transfected with peGFP-N3-IE86 were examined using a CCK8 assay. (B) Effects of hnRNP A2/B1 knockdown on the apoptosis of U251 cells. Cells transfected with peGFP-N3-IE86 were examined by flow cytometry. (C) Statistical analysis of (B). (D) The expression of caspase 3 of different groups was determined by Western blotting. The blots are representative of three independent experiments. (E) Statistical analysis of (D) *P < 0.05, **P < 0.01.