Figure 3.

The effects of lncRNA XIST and miR-204 on PaO₂/FiO₂ in lipopolysaccharide-induced acute respiratory distress syndrome. An acute respiratory distress syndrome (ARDS) model in mice was established in which mice were administered with lipopolysaccharide (LPS). Mice were divided into a negative control (NC) group, lncRNA XIST group, miR-204 inhibitors group, miR-204 mimics group, and IRF2 siRNA (si-IRF2) group, respectively. The PaO₂/FiO₂ ratio was measured in each group (*P < 0.05 vs. NC group).