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Isatin increases the protein expression of H3K4m1 (A and B) and PTEN (C and D) in SH-SY5Y cells after 48 h of treatment, as detected with a western blot analysis. Statistical analysis of RT-PCR data for the expression of PTEN mRNA (E). Values are expressed as mean ± SD. *P < 0.05, **P < 0.01 as compared with control.
