Table 1.
Characteristic | n | SLUG expression | P valuea | QKI expression | P valuea | ||
---|---|---|---|---|---|---|---|
|
|
||||||
Low | High | Low | High | ||||
Age (years) | |||||||
≤ 51 | 48 | 25 | 23 | 0.281 | 17 | 31 | 0.028* |
> 51 | 60 | 25 | 35 | 34 | 26 | ||
Tumor size (cm) | |||||||
≤ 2 | 72 | 32 | 40 | 0.585 | 37 | 35 | 0.220 |
> 2 | 36 | 18 | 18 | 14 | 22 | ||
Lymph node status | |||||||
Negative | 67 | 30 | 37 | 0.685 | 31 | 36 | 0.800 |
Positive | 41 | 20 | 21 | 20 | 21 | ||
ER status | |||||||
Negative | 21 | 7 | 14 | 0.184 | 9 | 12 | 0.655 |
Positive | 87 | 43 | 44 | 42 | 45 | ||
PR status | |||||||
Negative | 44 | 15 | 29 | 0.035* | 22 | 22 | 0.632 |
Positive | 64 | 35 | 29 | 29 | 35 | ||
HER-2 statusb | |||||||
Negative | 63 | 23 | 40 | 0.066 | 36 | 27 | 0.006* |
Positive | 38 | 21 | 17 | 11 | 27 | ||
Ki67 index | |||||||
≤ 14 | 63 | 32 | 31 | 0.267 | 24 | 21 | 0.282 |
> 14 | 45 | 18 | 27 | 27 | 36 | ||
Clinical TNM stage | |||||||
I~II | 90 | 43 | 47 | 0.490 | 44 | 46 | 0.438 |
III~IV | 18 | 7 | 11 | 7 | 11 | ||
Histologic grade | |||||||
I~II | 85 | 41 | 44 | 0.437 | 43 | 42 | 0.178 |
III | 3 | 9 | 14 | 8 | 15 | ||
Histologic type | |||||||
IDC | 84 | 32 | 52 | 0.001* | 37 | 47 | 0.216 |
Other | 24 | 18 | 6 | 14 | 10 | ||
E-cadherin | |||||||
Negative | 11 | 8 | 3 | 0.064 | 5 | 6 | 0.901 |
Positive | 97 | 42 | 55 | 46 | 51 | ||
Distant metastasis | |||||||
Negative | 99 | 48 | 51 | 0.172 | 49 | 50 | 0.177 |
Positive | 9 | 2 | 7 | 2 | 7 |
By Chi-square test.
There were 7 patients who had no results of HER2 FISH test and the IHC showed 2+ in history.
Statistically significant.