Table 3.
Univariate and multivariate analyses of the predictors of overall survival in HCC patients
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| HR | P > |z| | 95% CI | HR | P > |z| | 95% CI | |
| CA XII expression | ||||||
| High versus Low | 2.17 | 0.007* | 1.232-3.818 | 1.77 | 0.060 | 0.976-3.213 |
| Gender | ||||||
| Male versus Female | 1.65 | 0.221 | 0.740-3.672 | |||
| Age (years) | ||||||
| ≥ 60 versus < 60 | 1.27 | 0.445 | 0.684-2.372 | |||
| Tumor size (cm) | ||||||
| > 5 versus ≤ 5 | 1.88 | 0.029* | 1.068-3.315 | 1.50 | 0.183 | 0.826-2.713 |
| Tumor encapsulation | ||||||
| None versus Complete | 1.01 | 0.967 | 0.577-1.774 | |||
| Tumor number | ||||||
| Multiple versus Solitary | 1.56 | 0.197 | 0.795-3.053 | |||
| Hepatitis B virus infection | ||||||
| Yes versus No | 1.36 | 0.429 | 0.636-2.899 | |||
| Liver cirrhosis | ||||||
| Yes versus No | 1.26 | 0.576 | 0.563-2.805 | |||
| Pathologic grade | ||||||
| Grade 2 versus Grade 3 | 0.90 | 0.713 | 0.513-1.578 | |||
| TNM stage | ||||||
| Stage I versus Stage II | 0.51 | 0.020* | 0.287-0.898 | 0.57 | 0.053 | 0.319-1.007 |
*
P < 0.05.