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Nrf2 pathway was activated to resist oxidation. A. Western blotting showed the effect of drugs on total Nrf2 protein. B. Western blotting showed the effect of the drugs on cytoplasmic Nrf2 protein. C. Western blotting showed the effect of the drugs on nuclear Nrf2 protein. D. Real time PCR analysis of Nrf2 downstream ARE-containing mRNA was affected by lactose and/or NAC. *P<0.05, **P<0.01, ***P<0.001 (ANOVA): *Lactose versus vehicle.
