Figure 2.

Use of IR-783 dye in detection of human cervical tumor xenografts and metabolism pathway. A. Images of subcutaneous cervical cancer. Whole-body NIR imaging and X-ray radiography were captured after 24 h administration of IR-783. B. Frozen sections of the retrieved xenografts staining with DAPI demonstrated IR-783 dye specifically uptake by cancer cells and H&E staining of retrieved xenografts confirmed the existence of cancer cells. C. Host organs were dissected and subjected to ex vivo imaging for researching metabolism of IR-783 dye.