Figure 1.

lnc-NEAT1 expression in AECOPD, stable COPD, and healthy controls as well as ROC curves. Lnc-NEAT1 expression was higher in AECOPD patients thanin stable COPD patients or healthy controls, and it was also increased in stable COPD and healthy controls (A). According to ROC curve, lnc-NEAT1 distinguished AECOPD patients from stable COPD patients (B). ROC curves also showed that lnc-NEAT1 could distinguish AECOPD from healthy controls (C) and distinguish stable COPD from healthy controls (D). ROC curve and areas under the curve (AUC) were used to investigate the value of lncRNA NEAT1 in COPD diagnosis. P < 0.05 was considered significant. Lnc-NEAT1, long non-coding RNA nuclear enriched abundant transcript 1; AECOPD, acute exacerbation of chronic obstructive pulmonary disease; COPD, chronic obstructive pulmonary disease; ROC curve, receiver operating characteristic curve. Comparison between two groups was determined by Wilcoxon rank sum test.