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. 2019 Aug 1;12(8):2837–2848.

Figure 3.

Figure 3

Lnc-NEAT1 expression is positively correlated with inflammatory cytokines in AECOPD patients, stable COPD patients and healthy controls. Increased lnc-NEAT1 expression was associated with higher TNF-α, IL-1β, IL-6 and IL-17 levels in AECOPD patients (A-D). Higher lnc-NEAT1 expression correlated with raised TNF-α, IL-6 and IL-17 levels in stable COPD patients (E-H). Lnc-NEAT1 expression was positively correlated with TNF-α, IL-6 and IL-17 levels in healthy controls (I-L). Correlation of lnc-NEAT1 expression with inflammatory cytokines levels was determined by Spearman correlation analysis. P < 0.05 was considered significant. Lnc-NEAT1, long non-coding RNA nuclear enriched abundant transcript 1; AECOPD, acute exacerbation of chronic obstructive pulmonary disease; COPD, chronic obstructive pulmonary disease; TNF-α, tumor necrosis factor-α; IL-1β, interleukin-1β; IL-6, interleukin-6; IL-17, interleukin-17.