Figure 5.

miR-193a expression in AECOPD patients, stable COPD patients, and healthy controls, as well as ROC curves. miR-193a expression was lower in AECOPD patients compared to stable COPD patients and healthy controls, and it was also decreased in stable COPD patients compared to healthy controls (A). According to ROC curves, miR-193a could distinguish AECOPD from stable COPD (B) or healthy controls (C). Also, miR-193a could distinguish stable COPD from healthy controls (D). Comparison between two groups was determined by Wilcoxon rank sum test. ROC curve and areas under the curve (AUC) were used to investigate the value of miR-193a in COPD diagnosis. P < 0.05 was considered significant. AECOPD, acute exacerbation of chronic obstructive pulmonary disease; COPD, chronic obstructive pulmonary disease.