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. 2019 Oct 1;12(10):3740–3751.

Figure 2.

Figure 2

Over-expression of miR-145 inhibited proliferation and induced apoptosis in cervical cancer cells. A-E. Hela and SiHa cells were transfected with miR-NC or miR-145 mimic. A. The over-expression efficiency of miR-145 was detected by qRT-PCR. B, C. The cell ability of Hela and SiHa cells with over-expressed miR-145 was determined by MTT assay. D. The effect of miR-145 over-expression on cell apoptosis in transfected Hela and SiHa cells was confirmed by flow cytometry. E. Protein levels of apoptosis-related proteins in treated Hela and SiHa cells were analyzed using western blot. F. The tumor volume was examined every week. G. The tumor weight was measured at 6 weeks post injection. H. QRT-PCR was applied to detect WNT2B expression in Xenograft tumor model. **P < 0.01.