Table 3.
Multivariate analyses of clinicopathological variables affecting overall and disease-free survivals
| Clinicopathological variables | Overall survival | Disease-free survival | ||
|---|---|---|---|---|
|
|
|
|||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| NDRG3 expression, positive vs negative | 1.656 (1.125-2.437) | 0.011 | 1.432 (0.999-2.054) | 0.051 |
| Tumor size, > 2 cm vs ≤ 2 cm | 2.067 (1.464-2.919) | < 0.001 | 1.327 (0.992-1.774) | 0.057 |
| Histological grade, 3 vs 1&2 | 1.905 (1.342-2.703) | < 0.001 | 1.603 (1.186-2.166) | 0.002 |
| Lymph node metastasis, present vs absent | 1.754 (1.215-2.53) | 0.003 | 1.632 (1.182-2.253) | 0.003 |
| Lymphovascular invasion, present vs absent | 1.755 (1.2-2.567) | 0.004 | 1.938 (1.378-2.726) | < 0.001 |
HR, hazard ratio; CI, confidence interval.