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. 2019 Dec 4;11(12):2963. doi: 10.3390/nu11122963

Figure 8.

Figure 8

Rd and Rg3 exert anti-inflammatory activity via mTORC1-mediated M2 polarization. (A) Raw264.7 cells were incubated with LPS and CRG for 24 h. (B–I) RAW264.7 cells were pretreated with Rd or Rg3 for 3 h and then stimulated with LPS for 6 h. Expression of M1 marker genes (B) Ccl2; (C) Ccl5; (D) Il-1β; (E) Il-6; (F) iNos and (G) Tnf-α and (C) M2 marker genes (H) CD163 and (I) Il-10 were measured by qRT-PCR. * p < 0.05 versus vehicle (Veh), ** p < 0.01 versus Veh, *** p < 0.001 versus Veh, **** p < 0.0001 versus Veh.