Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of Nav1.5 currents by lidocaine (LID), tetrodotoxin (TTX) and an LID + TTX mixture. The structures of (A) TTX and (B) LID. (C) Representative traces were evoked by a single 15 ms depolarizing pulse to −10 mV from the holding potential of −130 mV in the absence (blank lines) or presence (red lines) of LID (100 μM), TTX (100 nM) or an LID (100 μM) + TTX (100 nM) mixture. (D) Inhibition rate of Nav1.5 by LID (100 μM), TTX (100 nM) or an LID (100 μM) + TTX (100 nM) mixture.
