Table 2.
Stability of formulations at 75% humidity (40 °C) or 90% humidity (25 °C).
| Groups | Appearance | Content (%) | Total Impurities (%) | |||
|---|---|---|---|---|---|---|
| (40 °C, 75%/25 °C, 90%) | TTX | LID | TTX | LID | ||
| TL001 | 0 day | White, cake shaped | 99.16/99.16 | 99.91/99.91 | 0.94/0.94 | 0.10/0.10 |
| 5 days | Partly shrunk/White, cake shaped | 98.90/99.13 | 99.89/99.89 | 1.15/0.81 | 0.10/0.10 | |
| 10 days | Completely shrunk/White, cake shaped | 98.75/99.14 | 99.90/99.89 | 1.20/0.81 | 0.10/0.10 | |
| TL002 | 0 day | White, cake shaped | 99.30/99.30 | 99.89/99.89 | 0.76/0.76 | 0.10/0.10 |
| 5 days | Partly shrunk/White, cake shaped | 98.61/99.19 | 99.88/99.89 | 1.40/0.80 | 0.10/0.11 | |
| 10 days | Completely shrunk/White, cake shaped | 98.40/99.24 | 99.90/99.87 | 1.67/0.89 | 0.30/0.11 | |
| TL003 | 0 day | White, cake shaped | 98.95/98.95 | 99.90/99.90 | 1.32/1.32 | 0.11/0.11 |
| 5 days | White, cake shaped | 98.11/98.76 | 99.88/99.90 | 1.74/1.34 | 0.12/0.11 | |
| 10 days | White, cake shaped | 97.64/98.64 | 99.88/99.88 | 1.87/1.43 | 0.12/0.12 | |
| TL004 | 0 day | White, cake shaped | 99.22/99.22 | 99.90/99.90 | 0.96/0.96 | 0.10/0.10 |
| 5 days | White, cake shaped | 98.67/98.66 | 99.90/99.89 | 1.39/1.34 | 0.11/0.11 | |
| 10 days | White, cake shaped | 97.96/98.56 | 99.86/99.89 | 2.35/1.45 | 0.13/0.11 | |