Table 3.
Neuropsychological scores in children aged 7–8 years according to serum ferritin (SF) levels (μg/L) measured in the first period of pregnancy. INMA cohort study, Spain 2003–2008.
| Groups of SF (μg /L) | p | Posthoc Analyses | |||
|---|---|---|---|---|---|
| <12.0 a Median (IQR) |
12.0–60.0 b Median (IQR) |
≥60.0 c Median (IQR) |
|||
| N-Back Test | |||||
| d’ numbers 1-back | 3.4 (3.3–3.6) | 3.4 (3.4–3.5) | 3.5 (3.4–3.6) | 0.744 | |
| d’ numbers 2-back | 1.6 (1.4–1.8) | 1.9 (1.8–1.9) | 1.9 (1.7–2.1) | 0.037 | 0.029 ab |
| d’ numbers 3-back | 1.0 (0.86–1.17) | 1.1 (1.0–1.1) | 1.1 (1.0–1.3) | 0.691 | |
| Attention Network Test | |||||
| Omission errors | 4.9 (3.5–6.2) | 4.8 (4.3–5.3) | 5.0 (3.8–6.1) | 0.963 | |
| HRT-SE | 317.4 (306.2–328.8) | 316.0 (310.8–321.3) | 316.1 (303.5–328.8) | 0.979 | |
| Trail Making Test | |||||
| Response time TMT A | 78.8 (70.9–86.7) | 71.5 (69.3–73.7) | 72.1 (68.1–76.1) | 0.050 | 0.041 ab |
| Response time TMT B | 77.9 (71.5–84.3) | 73.9 (71.7–76.2) | 74.0 (69.0–79.1) | 0.413 | |
p-values are from Kruskal–Wallis test; IQR: Inter Quartile Range; HRT SE: Hit reaction time standard error; a Ferritin levels in the first period of pregnancy <12.0 μg/L; b Ferritin levels in the first period of pregnancy 12.0–60.0 μg/L; c Ferritin level in the first period of pregnancy >60.0 μg/L; a,b Differences between groups.