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Signaling pathways involved in melanin synthesis. Tyrosinase-related protein (TRP), microphthalmia-associated transcription factor (MITF), adenosine 3′,5′-cyclic monophosphate (cyclic AMP) (cAMP), cAMP response element-binding (CREB), extracellular receptor kinase (ERK), melanocortin 1 receptor (MC1R), wingless-related integration site (Wnt), α-melanocyte-stimulating hormone (MSH), agonist stimulating protein (ASP), and stem cell factor (SCF).
