PES	Polyether sulfone
xRC	Cross-linked regenerated cellulose
A	Membrane area (m2)
V	Permeate volume (m3)
t	Time (s)
J	Flux (m3 m−2 s−1)
µ	Dynamic viscosity (N m−2 s)
${\mathrm{p}}_{\mathrm{f}}$	Feed pressure (Pa)
${\mathrm{p}}_{\mathrm{r}}$	Retentate pressure (Pa)
${\mathrm{p}}_{\mathrm{p}}$	Permeate pressure (Pa)
TMP	Transmembrane pressure (Pa)
${\mathrm{R}}_{\mathrm{total}}$	Total membrane resistance (m−1)
${\mathrm{R}}_{\mathrm{m}}$	Membrane resistance (m−1)
${\mathrm{R}}_{\mathrm{f}}$	Fouling resistance (m−1)
SCM	Serum-containing medium
SFM	Serum free medium,
HCP	Host cell proteins
hcDNA	Host cell DNA
LP	Hydraulic permeability (L m−2 h−1 bar−1)
Jw, J0	Pure water flux (L m−2 h−1)
α	Permeability
m	Fouling constant (-)
k	Resistance coefficient
c	Concentration (feed, permeate, retentate)
c0	Initial concentration
ci	Concentration at a specific concentration factor (cf)
cf	Concentration factor (-)
$\widehat{{\mathrm{y}}_{\mathrm{i}}}$	y-value of the model function
${\mathrm{y}}_{\mathrm{i}}$	y-value of the experimental data
kcf	Fouling constant – cake filtration
kib	Fouling constant – intermediate blocking
ksb	Fouling constant – standard blocking
kcb	Fouling constant – complete blocking
Re	Reynolds number (-)
SSE	Sum square error
Rfit2	Coefficient of determination
MWCO	Molecular weight cut-off (kDa)
n.d.	not determined