Table 1.
Demographic characteristics of Mexican women used in the study.
| Proteomic Analysis | ELISA | |||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | Normal NOR (n = 10) | Osteopenic OS (n = 10) | Osteoporotic OP (n = 10) | p Value | Normal NOR (n = 26) | Osteopenic OS (n = 29) | Osteoporotic OP (n = 19) | p Value |
| Age (years) * | 73 (2) | 74 (3) | 75 (4) | 0.8 | 65 (8) | 67 (7) | 73 (9) | <0.001 |
| Weight (kg) * | 56 (5) | 52 (6) | 56 (4) | 0.3 | 63 (12) | 62 (12) | 54 (8) | 0.1 |
| Height (cm) * | 153 (5) | 151 (4) | 148 (6) | 0.07 | 152 (6) | 152 (5) | 148 (7) | 0.09 |
| BMI (kg/m) * | 24 (1) | 23 (2) | 25 (2) | 0.8 | 27 (5) | 27 (4) | 25 (3) | 0.3 |
| Waist circumference (cm) * | 90 (6) | 88 (8) | 94 (7) | 0.1 | 95 (11) | 95 (10) | 92 (10) | 0.5 |
| Body fat proportion * | 41 (7) | 40 (3) | 43 (6) | 0.6 | 44 (6) | 45 (6) | 40 (8) | 0.08 |
| Never smoker, % | 80 | 90 | 80 | 0.9 | 69 | 66 | 79 | 0.9 |
| Smoking Current, % | 3.9 | 14 | 5.3 | |||||
| Uric acid (mg/dL) * | 5 (2) | 5 (1) | 6 (1) | 0.4 | 5 (1) | 5 (1) | 5 (1) | 0.5 |
| Systolic blood pressure (mmHg) * | 130 (15) | 132 (26) | 132 (30) | 0.8 | 131 (17) | 134 (21) | 135 (31) | 0.5 |
| Diastolic blood pressure (mmHg) * | 71 (13) | 72 (12) | 71 (10) | 1 | 74 (12) | 76 (9) | 72 (10) | 0.7 |
| Total cholesterol (mg/dL) * | 147 (79) | 120 (64) | 149 (57) | 0.6 | 129 (65) | 131 (80) | 172 (98) | 0.3 |
| Triglycerides (mg/dL) ** | 172 (110–326) | 175 (108–192) | 138 (107–177) | 0.4 | 168 (110–277) | 129 (102–173) | 141 (109–177) | 0.07 |
| LDL-C(mg/dL) * | 123 (33) | 145 (40) | 120 (37) | 0.9 | 136 (34) | 126 (35) | 127 (43) | 0.9 |
| HDL-C(mg/dL) * | 43 (9) | 54(10) | 50 (9) | 0.04 | 48 (12) | 53 (11) | 53 (16) | 0.12 |
| Glucose (mg/dL) ** | 108 (94–150) | 98(87–104) | 94 (92–103) | 0.3 | 103 (95–129) | 99 (89–106) | 93 (89–101) | 0.048 |
| Hip BMD (g/cm2) | 0.95 (0.06) | 0.78 (0.04) | 0.65 (0.03) | <0.001 | 0.97 (0.03) | 0.81 (0.02) | 0.68 (0.04) | <0.001 |
| Hip T-score | −0.49 (0.45) | −1.84 (0.32) | −2.83 (0.24) | <0.001 | −0.33 (0.25) | −1.59 (0.20) | −2.94 (0.33) | <0.001 |
| Lumbar Spine BMD (g/cm2) ** | 1.35 (0.91, 1.12) | 0.87 (0.79, 0.95) | 0.79 (0.78, 0.92) | 0.03 | 1.03 (0.92, 1.09) | 0.91 (0.87, 1.04) | 0.79 (0.74, 0.92) | 0.001 |
| Lumbar Spine T-score ** | −1.37 (−2.11, −1.01) | −2.59 (−3.36, −1.65) | −3.31 (−3.44, −2.41) | 0.02 | −1.49 (−2.14, −0.97) | −2.39 (−2.80, −1.38) | −3.40 (−3.74, −2.41) | <0.001 |
* Mean (SD), ** Median (P25, P75). The differences between groups for continuous variables were analyzed by Analysis of variance (ANOVA) or Dunn test. For the categorical variables tests of proportions were used.