Table 4.

Minimal mouse lethal doses of tetanus toxin in ng/kg in different mammals and different routes of administration ^a.

Way of Inoculation	Mouse	Guinea Pig	Rabbit	Cat	Dog	Goat	Sheep	Horse	Monkey	Human
intramuscular (im)	0.15	0.2	3	600	150	0.24	0.4	0.2	0.4	0.2 b
intravenous (iv)		0.2	12	480	240				2
intraperitoneal (ip)	0.15
subcutaneous (sc)		0.2	12
intraventricular		0.2	12
intra-sciatic nerve			1.2						0.25
intra-spinal cord			0.12	2.0	0.1
intra-medulla			0.012		0.15
intra-ventriculum		0.1–0.2	1.2

^a Adapted from [17,47,81,84,85,86]; data have been converted into nanograms/kilograms for a better comparison. ^b TeNT toxicity value for humans is the results of extrapolation from monkey data [6] and from records of accidental inoculations quoted by [47].