Table 1.

Large animal selective hypothermia experiments

Author	Method	Species	Ischemia type	Total n	NT	sHT	T to TT (min)	TT(°C)
Lougheed and Kahn[3]	Bypass	Canine	Global	6		6	15-20	20
Schwartz et al.[24]	Bypass	Baboon		12		12	26±13	18.5
Schwartz et al.[25]	Bypass	Baboon	Focal	8	4	4	12±4	27
Mori et al.[12]	Bypass	Swine	Global	12	6	6	60-120	32
Zhang et al.[40]	Epidural	Swine	Focal	12	6	6	5	28
Verdura et al.[10]	Bypass	Canine	Global	21	5	16	35	15
Mattingly et al.[39]	Endovascular Bypass	Swine	Focal	25	13	12	25	<30
Cattaneo et al.[41]	Cooling catheter	Sheep	None			8	180	33
Wang et al.[42]	ICS	Monkey	None	4		4	10	33

TT: Target temperature, T to TT: Time to TT, NT: Normothermia, sHT: Selective hypothermia, ICS: Ice-cold saline