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. 2019 Nov 24;11(12):2871. doi: 10.3390/nu11122871

Table 2.

Mitochondrial response to the NAFLD-inducing diets.

Mitochondrial Response Alterations Diet Reference
Mitochondrial fatty acid β-oxidation (TCA cycle)/tricarboxylic acid (TCA) cycle Induction High fat (lard; soybean oil) [191]
High fat (lard) [194]
High fat (lard; soybean oil) [195]
High fructose [196]
High fat (lard or fish oil) [159]
Respiratory activity Reduction High fat (palm oil) [197]
Choline deficient diet [198]
High fat (lard) [199]
High fat (lard or fish oil) [159]
High fat (butter (C16:0, C18:0)) [200]
High fat (lard; soybean oil) [117]
Induction High fat (lard; soybean oil) [201]
High fat (lard; soybean oil) [191]
Oxidative phosphorylation (OXPHOS) complexes activity Reduction High fat [202]
High fat (lard; soybean oil) (45% saturated fatty acids (FAs)) [196]
Choline deficient diet [198]
High fat (61% saturated FAs) and sucrose [203]
Maintenance High fat (lard) [199]
Induction High fat (lard; soybean oil) [191]
High fructose [196]
Mitochondrial
ATP production
Reduction High fat (vegetable oil) and fructose and glucose [165]
High fat (lard; soybean oil) [117]
Induction High fat (lard; soybean oil) [191]
High fat (lard) [199]
Mitochondrial DNA Reduction High fat (61% saturated FAs) and sucrose [203]
High fat (coconut and soybean oil) and sucrose [204]
Maintenance High fat (lard) [199]
Induction High fat (lard; soybean oil) [201]