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. 2019 Dec 10;11(12):1141. doi: 10.3390/v11121141

Figure 6.

Figure 6

Rep protein enhances the binding activities of p50 and Sp1 with the il10 promoter at the later phase of PCV2 infection. (A–D) PAMs were infected with 5 MOI PCV1, PCV2, PCV2-Rep1, and PCV1-Rep2, and the binding activities of p50 and Sp1 were detected at 12 h, 24 h, and 48 h using the ChIP assay (A,B); the relevant statistical results of (A,B) are shown in line graphs (C,D). The data of (A,B) are representative of three independent experiments. The data of (C,D) are the means ± SD of three independent experiments. **p < 0.01 represents the PCV2-inoculated cells versus the PCV1-Rep2-inoculated cells at the same infection time point. #p < 0.05 represents the PCV2-inoculated cells versus the PCV2-Rep1-inoculated cells at the same infection time point. &p < 0.05 versus PCV1-inoculated cells at the same infection time point.