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. 2019 Dec 16;11(12):3072. doi: 10.3390/nu11123072

Figure 2.

Figure 2

The effects of dietary protein, dietary calcium and CaSR allosteric modulators on colon length and clinical score of colitis. Colon lengths of colitic mice and no-DSS controls fed with different diets (a) or treated with CaSR allosteric modulators (b). Clinical score of colitic mice fed with different diets (c) or treated with CaSR allosteric modulators (d) Clinical score is based on (1) general appearance, (2) weight loss, (3) behavior (4) blood in stool. Area under the curve of the cumulative clinical score of colitic mice fed with different diets (e) or treated with CaSR allosteric modulators (f). Statistical significance was determined by one-way ANOVA or Kruskal–Wallis for ranked clinical scores. * p < 0.05, ** p < 0.01 and *** p < 0.001 were regarded as statistically significant. Data are presented as the mean ± SEM, n = 10 and 25 mice per group, for the diets and modulators experiments, respectively.