Fig. 6.

The correlation between the levels of miR-124-3p and PRAS40 protein. a. ISH staining of miR-124-3p and IHC staining of PRAS40 and p-PRAS40 were performed in 49 clinical HCC specimens in Cohort 3 (same samples used in Fig. 1G-H). Scale bars, 100μm. b. Correlation analyses between the staining scores of miR-124-3p and PRAS40 or p-PRAS40, P value is calculated by Fisher's exact test and a Pearson correlation coefficient (r) is shown. c. Real time PCR in the peri‑cancer and HCC samples of Akt1s1^+/+ mice, n = 6. The experiments were performed in triplicate. Bars, SD. *, P<0.05; **, P<0.01 (Student's t-test).