Table 1.

Cases of CHD2 mutations with behavioral disorders: main psychiatric and cognitive characteristics

Reference	Number of patients	Gender M/F	Mean Age (years)	Behavioral features (Number)	Cognitive profile	Brain MRI
[5]	6	4/6	14,5	ASD (2)	Moderate ID (2) Severe ID (4)	NA
[11]	4	NA	NA	ASD (4)	Cognitive impairment (4)	NA
[14]	9 (+ 1deletion)	6/4	17,9	ASD (4) ADHD (1) Challenging behavior (8) Psychotic features (1)	Mild to severe (10)	Progressive atrophy (3) Corpus callosum atrophy (3) Normal during adulthood (2)
[15]	2	2/0	NA	ASD	Mild d ID (1/2)	NA
[16]	1	1/0	26	Hyperactivit Autistic features	Severe ID	Normal
[17]	2	2/0		ASD Hyperactivity Developpemental delay Bruxism Stereotypic movements		NA
[18]	1	0/1	27	Limited social skills Psychotic disorder	Moderate ID	NA