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Main cardiovascular phenotypic information in two subgroups of LDS
| TGFBR1/TGFBR2/SMAD3 | TGFB2/TGFB3/SMAD2 | |||||
|---|---|---|---|---|---|---|
| LP/P | VUSLP | VUS | LP/P | VUSLP | VUS | |
| Numbers | 26 | 2 | 20 | 3 | 1 | 3 |
| Age, years | 29.5 ± 13.3 | 34.0 ± 4.2 | 38.0 ± 11.5 | 20.3 ± 10.4 | 20 | 43.0 ± 8.5 |
| Normal or mild dilation | 3 | 0 | 4 | 3 | 0 | 0 |
| Surgery due to an aortic aneurysm/valve disease | 8 | 0 | 8 | 0 | 1 | 0 |
| Aortic dissection and related death | 15 | 2 | 8 | 0 | 0 | 3 |
