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. 2020 Jan 8;20:17. doi: 10.1186/s12886-020-1304-x

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Examples of eyes included in this study. A Normal-appearing optic nerve head with intact rim and RNFL (A1), intact GCC (A3), dense macular microvascular network (A2), and normal VF (A4) in normal eyes. Enlarged vertical cup-to-disc ratio with focal rim notching and RNFL defect (B1, C1), focal defects of macular microvascular network (B2, C2) matching the location of GCC loss (B3, C3) with normal VF (B4) in pre-perimetric glaucoma or with typical glaucomatous VF defects (C4) in early perimetric glaucoma. GCC, ganglion cell complex thickness. RNFL, peripapillary retinal nerve fiber layer; VF, visual field