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. 2020 Jan 8;20:17. doi: 10.1186/s12886-020-1304-x

Table 2.

GCC thickness in normal, pre-perimetric and early perimetric glaucoma eyes (Mean ± SD)

GCC thickness (μm) P value (univariate, multivariate)
normal PPG early PG a b
Global 103.4 ± 5.6 92.4 ± 7.9 80.7 ± 10.9 < 0.001, < 0.001 < 0.001, < 0.001
Global SH 103.2 ± 5.6 93.6 ± 8.2 84.2 ± 12.3 < 0.001, < 0.001 < 0.001, 0.001
Global IH 103.6 ± 6.0 91.2 ± 9.4 77.1 ± 12.4 < 0.001, < 0.001 < 0.001, < 0.001
Regional
 Para 110.4 ± 8.5 103.9 ± 9.7 89.2 ± 15.9 0.010, < 0.001 < 0.001, < 0.001
 Para T 102.5 ± 7.9 96.3 ± 10.5 81.3 ± 13.5 0.015, 0.001 < 0.001, < 0.001
 Para S 113.2 ± 9.1 105.6 ± 10.7 93.4 ± 16.0 0.005, 0.001 < 0.001, 0.001
 Para N 111.6 ± 9.5 107.1 ± 8.0 92.5 ± 18.7 0.058, < 0.001 < 0.001, < 0.001
 Para I 114.3 ± 8.6 106.8 ± 11.5 89.5 ± 20.3 0.007, < 0.001 < 0.001, < 0.001
 Peri 103.2 ± 5.7 90.6 ± 8.0 79.5 ± 10.5 < 0.001, < 0.001 < 0.001, < 0.001
 Peri T 87.2 ± 4.2 76.4 ± 7.7 68.2 ± 7.9 < 0.001, < 0.001 < 0.001, < 0.001
 Peri S 103.1 ± 7.2 90.0 ± 9.8 80.9 ± 14.1 < 0.001, < 0.001 < 0.001, 0.002
 Peri N 121.1 ± 7.7 111.2 ± 8.8 98.9 ± 14.4 < 0.001, < 0.001 < 0.001, 0.001
 Peri I 101.6 ± 7.3 84.9 ± 11.7 70.1 ± 13.0 < 0.001, < 0.001 < 0.001, < 0.001

Univariate and multivariate analyses using mixed effects model with adjustment for age, gender, and SSI were used to for comparison. The Bonferroni-corrected significance level (0.025) was used for multiple comparisons

GCC Ganglion cell complex, PPG Pre-perimetric glaucoma, PG Perimetric glaucoma, SH Superior hemifield, IH Inferior hemifield, para Parafoveal, peri Perifoveal, T Temporal, S Superior, N Nasal, I Inferior

a. Comparison between the PPG and normal group

b. Comparison between the early PG and normal group