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. 2020 Jan 8;17:11. doi: 10.1186/s12974-019-1670-6

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Plasma levels of α-synuclein in PD patients and healthy controls and the correlation with clinical characteristics. a Measurement of α-synuclein concentration by MSD immunoassay in plasma from PD (solid diamond) and normal control (solid circles) subjects. n = 24 for control, n = 43 for PD groups respectively. Data are expressed as mean ± SEM, one-way ANOVA. b Correlation of α-synuclein levels in plasma from PD patients with H-Y stage. c Correlation of α-synuclein levels in plasma from PD patients with UPDRS part I scores. d Correlation of α-synuclein levels in plasma from PD patients with UPDRS part III scores. The correlation was established by calculating correlation coefficients