Table 2.

Effect Estimates and Standard Error of COMT rs4818 (Per G Allele) and rs4680 (Per Val Allele) Association With Baseline Fibrinogen Levels (mg/dL) in Gene‐Dosage Models

SNP	Sex	All			White			Black			Hispanic			Asian
		β	SE	P Value	β	SE	P Value	β	SE	P Value	β	SE	P Value	β	SE	P Value
rs4818	All	−3.65	1.35	0.007	−0.81	2.11	0.70	−2.29	3.03	0.45	−4.94	3.02	0.10	−9.70	3.06	0.002
	Women	−5.29	1.93	0.01	−4.70	4.69	0.32	−2.92	4.40	0.51	−3.78	2.89	0.19	−11.76	4.42	0.01
	Men	−2.28	2.98	0.44	−0.42	4.35	0.92	−8.00	4.46	0.07	3.53	2.80	0.21	−6.90	4.53	0.13
rs4680	All	0.53	1.29	0.68	0.84	1.96	0.67	1.70	2.78	0.54	−1.43	2.89	0.62	0.54	3.31	0.87
	Women	−2.98	1.83	0.10	−3.05	2.81	0.28	−0.44	4.09	0.92	−7.68	4.00	0.06	−0.02	4.45	0.99
	Men	4.19	1.75	0.02	5.05	2.69	0.06	4.01	3.71	0.28	5.09	4.08	0.21	1.37	4.20	0.74

COMT indicates catechol‐O‐methyltransferase; SNP, single nucleotide polymorphism.