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HIF-1α was a target gene of miR-155. The expression of HIF-1α in SKOV3 cells was measured by (A) qRT-PCR and (B) Western blot; (C) The binding site between miR-155 and HIF-1α was on the 3′UTR; (D) The binding of miR-155 with HIF-1α was verified by luciferase reporter gene assay; * P<0.05, ** P<0.01, compared inhibitor NC group or mimic NC+wt-HIF-1α group; NC – negative control.
