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. 2019 Dec 30;25:10164–10172. doi: 10.12659/MSM.919112

Figure 5.

Figure 5

DMED regulates miR-155-HIF-1α axis to mediate cell proliferation, apoptosis, migration, and invasion of OC cells. (A) Cell proliferation was inspected by CCK-8 assay; (B) Cell apoptosis was determined with flow cytometry; (C, D) The mRNA and protein expression levels of caspase-3 and Mcl-1 were separately detected by qRT-PCR and Western blot; (E) Cell migration was detected by wound healing assay; (F) Cell invasion was determined using Transwell assay; * P<0.05, ** P<0.01, compared to DMED group; # P<0.05, ## P<0.01, compared to DMED+si-HIF-1α group; DMED – dexmedetomidine.