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. 2019 Dec 19;10:2949. doi: 10.3389/fimmu.2019.02949

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Copyright © 2019 Rinaldi, Consonni, Cordiglieri, Sacco, Crasà, Fontana, Morelli, Elli, Mantegazza and Baggi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Therapeutic administration of vital bifidobacteria strains ameliorates EAMG course. (A) Clinical EAMG score (mean ± SEM) of EAMG animals treated with vehicle, LBmix or BBmix (n = 6 rats/group). (B) Clinical EAMG score (mean ± SEM) of EAMG animals treated with vehicle, BBmix heat exposed or BBmix vital (n = 11 rats/group). (C,D) Anti-rat AChR Ab serum titer (pmol/ml of rat serum, mean ± SD) of treated-EAMG rats. Two-way ANOVA test with Tukey's post-hoc test for multiple-comparisons was used for clinical score. One-way ANOVA test with Dunnett's multiple comparison test was used for anti-rat AChR. Corrected p-values are reported.