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. 2019 Oct 25;13(1):204–211. doi: 10.1111/cts.12706

Figure 1.

Figure 1

Model diagram. Ap, amount of AVB‐S6‐500 in the plasma compartment; At, amount of AVB‐S6‐500 in the peripheral compartment; CL, systemic clearance; KM, concentration of serum AVB‐S6‐500 at half‐maximal removal by the target; Q, intercompartmental clearance; VC, volume of the central/plasma compartment; Vmax, maximal removal rate of AVB‐S6‐500 from the serum; VP, volume of the peripheral compartment.