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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: J Affect Disord. 2019 Feb 19;249:347–356. doi: 10.1016/j.jad.2019.02.051

Figure 2.

Figure 2.

Fluoxetine (FLX; 20 mg/kg) exposure during adolescence (PD35–49) did not influence responses to a novel object recognition test in adulthood (n= 10–11/group), in either male (top panels) or female (bottom panels) C57BL/6 mice. Adult mice pretreated with FLX during adolescence did not differ in the latency (sec) to initially approach (males, A; females, D), or the total time spent exploring a novel object, when compared to respective (VEH) pre-treated controls (males, B; females, E). No differences in total locomotor activity were observed as a function of antidepressant pre-exposure (males, C; females, F). Data are presented as mean ± SEM.