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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: J Affect Disord. 2019 Feb 19;249:347–356. doi: 10.1016/j.jad.2019.02.051

Figure 6.

Figure 6.

Enduring effects of fluoxetine (20 mg/kg) exposure on body weight. (A) When compared to controls (VEH), FLX-exposed adolescent male mice displayed lower weight gain as of the second day of antidepressant exposure (PD36), remaining lower until PD49. Twenty-one days after FLX treatment (PD70), no differences in body weight were noted between the groups. (B) Similarly, adolescent female c57BL/6 mice displayed lower body weight 24 h after the beginning of FLX treatment (PD36), when compared to controls. On PD70 (21 days after the last day of FLX exposure), no differences in body weight were apparent between the groups. (C) When compared to VEH-pretreated mice, adult FLX-exposed mice displayed lower body weight as of the third day of treatment (PD72). Twenty-one days after the last day of FLX exposure (PD105), no differences in body weight between the groups were observed. Data are presented as mean + SEM. *Significantly different when compared to VEH (p<0.05). Arrow indicates 21 days of drug washout.