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. 2019 Dec 27;18:73–82. doi: 10.1016/j.csbj.2019.12.009

Fig. 3.

Fig. 3

Histological examination of retinal structures in morphants of ankrd33aa and ankrd33ab. (A) The eye section of control MO-injected embryos. The retina of all control embryos (13/13) showed well-structured lamination. (B,C,D) Eye sections of ankrd33aa morphant embryos. The retina of ankrd33aa morphant embryos could be (B) normal (2/13), (C) disorganized in plexiform layers (9/13), or (D) severely degenerated (2/13). (E,F) Eye sections of ankrd33ab morphant embryos. The retina of ankrd33ab morphant embryos could be (E) normal (7/16) or (F) underdeveloped with an enucleation defect in lens fiber cells (yellow arrows) (9/16). In (A–F), coronal sections of the eye were performed to reveal retinal lamination by hematoxylin and eosin staining. The area within yellow rectangle is enlarged to show the retina structure. The anterior is to the top. Scale bars: 20 μm. RPE: retinal pigment epithelium; PCL: photoreceptor cell layer; ONL: outer nuclear layer; OPL: outer plexiform layer; INL: inner nuclear layer; IPL: inner plexiform layer; GCL: ganglion cell layer. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)