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. 2019 Oct 25;13(1):147–156. doi: 10.1111/cts.12695

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© 2019 The Authors. Clinical and Translational Science published by Wiley Periodicals, Inc. on behalf of the American Society for Clinical Pharmacology and Therapeutics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Comparison between current and revised Clinical Pharmacogenetics Implementation Consortium (CPIC) genotype to phenotype translation tables for dextromethorphan and metoprolol. Dextrorphan formation rate by phenotype (IM, intermediate metabolizer; NM, normal metabolizer; PM, poor metabolizer; UM, ultrarapid metabolizer) assigned with current (a) and revised (c) CPIC definitions; alpha‐hydroxymetoprolol formation rate by phenotype assigned with current (b) and revised (d) CPIC definitions. Boxes represent interquartile range with interior line representing the median. Error bars represent 1.5× the interquartile range. Number of samples in each phenotype category is given in parentheses.