Table 1.
Distribution of CYP2D6 haplotypes (n = 628) identified in liver bank samples
| Allele | n (%) | Activity |
|---|---|---|
| SNVs and indels | ||
| *1 | 201 (32.0%) | Normal |
| *2 | 90 (14.3%) | Normal |
| *33 | 5 (0.8%) | Normal |
| *34 | 1 (0.2%) | Normal |
| *35 | 37 (5.9%) | Normal |
| *39 | 1 (0.2%) | Normal |
| *43 | 2 (0.3%) | Normal |
| *9 | 22 (3.5%) | Decreased |
| *10 | 15 (2.4%) | Decreased |
| *17 | 4 (0.6%) | Decreased |
| *29 | 1 (0.2%) | Decreased |
| *41 | 70 (11.1%) | Decreased |
| *59 | 5 (0.8%) | Decreased |
| *3 | 7 (1.1%) | None |
| *4 | 85 (13.5%) | None |
| *6 | 6 (1.0%) | None |
| *20 | 3 (0.5%) | None |
| Structural variants | ||
| *1 x 2 | 3 (0.5%) | Increased |
| *2 x 2 | 3 (0.5%) | Increased |
| *41 x 2 | 1 (0.2%) | Normal |
| *13 + *2 | 1 (0.2%) | Normal |
| *36 + *10 | 2 (0.3%) | Decreased |
| *4N + *4 | 4 (0.6%) | None |
| *68 + *4 | 35 (5.6%) | None |
| *5 | 24 (3.8%) | None |
SNV, single nucleotide variation.