Effect of G-1 on ISO-induced increases in myocardial contraction. A, LVP measured in an anesthetized rat using a direct LV pressure probe. ISO and G-1 were injected via a via a jugular catheter as indicated (arrows). B–D, 1-second strips of regular LVP and corresponding dp/dt at baseline, during ISO response, and after injection of G-1, respectively. Data are representative of n = 4 animals.