Table 1. Demographics and Clinical data for studied participants.
| Characteristics | Total | Cognitively unimpaired | Cognitive impairment | P Value§ |
|---|---|---|---|---|
| n = 613 | n = 117 | n = 496 | ||
| Age (years) | 63.7±7.8 | 59.3±7.7 | 64.7±7.4 | < 0.001 |
| Female sex | 258(42.1%) | 47(40.2%) | 211(42.5%) | 0.641 |
| Education level | 0.001 | |||
| ≤12 years | 444(72.4%) | 69(59.0%) | 375(75.6%) | |
| >12 years | 169(27.6%) | 48(41.0%) | 121(24.4%) | |
| Medical history | ||||
| Smoking | 270(44.0%) | 51(43.6%) | 219(44.2%) | 0.925 |
| Alcohol intake | 261(42.6%) | 51(43.6%) | 210(42.3%) | 0.936 |
| Diabetes | 231(37.7%) | 33(28.2%) | 198(39.9%) | 0.019 |
| Hypertension | 545(88.9%) | 95(81.2%) | 450(90.7%) | 0.003 |
| Stroke | 100(16.3%) | 6(5.1%) | 94(19.0%) | <0.001 |
| CHD | 193(31.5%) | 36(30.8%) | 157(31.7%) | 0.853 |
| BMI (kg/m2) | 23.6±4.1 | 24.2±5.8 | 23.5±3.6 | 0.202 |
| Dialysis vintage (months) | 57.0(24.0,101.5) | 42.0(12.0,78.0) | 60.0(29.0,104.8) | <0.001 |
| spKt/V | 1.5±0.5 | 1.4±0.3 | 1.5±0.5 | 0.246 |
| Lab. examination | ||||
| Hb (g/L) | 111.1±14.6 | 110.7±15.3 | 111.2±14.5 | 0.737 |
| Alb (g/L) | 39.9±3.2 | 40.3±2.5 | 39.9±3.3 | 0.218 |
| Calcium (mmol/L) | 2.2±0.2 | 2.2±0.2 | 2.2±0.3 | 0.127 |
| Phosphate (mmol/L) | 1.7±0.7 | 1.8±0.7 | 1.7±0.6 | 0.342 |
| iPTH (pg/mL) | 187.6(103.5,358.2) | 167.6(107.0,311.5) | 201.8(103.4,372.2) | 0.058 |
| Depression scores | 4.0(1.0,7.0) | 4.0(2.0,7.0) | 3.0(1.0,7.0) | 0.441 |
| MoCA-BJ scores | 21.0(19.0,23.0) | 25.0(23.5,26.0) | 21.0(18.0,22.0) | <0.001 |
| MMSE scores | 25.0(23.0,27.0) | 27.0(26.0,29.0) | 25.0(23.0,26.0) | <0.001 |
Values are presented as the mean ± SD for normally distributed continuous variables, median (interquartile range) for non-normally distributed continuous variables, and n (%) for categorical variables.
§ Normally distributed variables were compared using the Student’s t-test, and non-normal distributed variables were compared using the Mann-Whitney U test. Categorical variables are presented as percentages and were compared using the Chi-square test.
Abbreviations: CHD, coronary heart disease; BMI, body mass index; spKt/V, single-pool Kt/V; Hb, hemoglobin; Alb, albumin; iPTH, intact parathyroid hormone; MoCA, Montreal Cognitive Assessment; MMSE, Mini-Mental State Examination.