Table 4. Discriminant validity of the Beijing version of the Montreal Cognitive Assessment and the Mini-Mental State Examination for detecting cognitive impairment.
MoCA | MMSE | ||||||||
---|---|---|---|---|---|---|---|---|---|
Cutoff ≤ | Sen | Spe | PPV | NPV | Cutoff ≤ | Sen | Spe | PPV | NPV |
20 | 0.345 | 0.983 | 0.988 | 0.261 | 20 | 0.101 | 1.000 | 1.000 | 0.208 |
21 | 0.492 | 0.983 | 0.992 | 0.313 | 21 | 0.111 | 1.000 | 1.000 | 0.210 |
22 | 0.657 | 0.880 | 0.959 | 0.377 | 22 | 0.169 | 1.000 | 1.000 | 0.221 |
23 | 0.806 | 0.803 | 0.946 | 0.495 | 23 | 0.234 | 1.00 | 1.000 | 0.235 |
24† | 0.877 | 0.752 | 0.938 | 0.591 | 24 | 0.371 | 1.000 | 1.000 | 0.273 |
25 | 0.942 | 0.598 | 0.909 | 0.707 | 25 | 0.498 | 0.897 | 0.954 | 0.297 |
26 | 0.988 | 0.393 | 0.873 | 0.885 | 26† | 0.704 | 0.769 | 0.928 | 0.380 |
27 | 1.000 | 0.222 | 0.845 | 1.000 | 27 | 0.792 | 0.701 | 0.918 | 0.443 |
28 | 1.000 | 0.103 | 0.825 | 1.000 | 28 | 0.869 | 0.470 | 0.874 | 0.458 |
29 | 1.000 | 0.103 | 0.825 | 1.000 | 29 | 0.946 | 0.299 | 0.851 | 0.565 |
Abbreviations: MoCA, Montreal Cognitive Assessment; MMSE, Mini-Mental State Examination; Sen, Sensitivity; Spe, Specificity; PPV, positive predictive value; NPV, negative predictive value.
† Optimal cutoff score determined using Youden’s index.