Fig 4. Il11^SMC mice exhibit activated ERK1/2 signaling across organs.

Immunoblots of IL11 expression, phospho- (p) and total ERK1/2 and STAT3 protein in (a) colon, (b) heart, (c) liver, (d) lung, (e) kidney, (f) skin tissue of Il11^SMC mice treated with vehicle (veh) or tamoxifen (tam) (n = 3 per group). Dotted boxes in the immunoblots represent the veh-treated (black) and tam-treated (red) groups for all organs. All comparisons were conducted in organs harvested from mice 14 days post-veh or tam treatment.