Table 2. DBA/1J mortality after serial infection with SW293.
Method | Passage | No. of dead mice / No. of total mice | Mortality (%) | ||
---|---|---|---|---|---|
Total dead mice | Found dead mice | Euthanized mice | |||
Lung-Cell-Lung | 0 | 0/3 | 0/3 | 0/3 | 0 |
1 | 0/2 | 0/2 | 0/2 | 0 | |
2 | 2/3 | 0/3 | 2/3 | 66.67 | |
3 | 5/5 | 0/5 | 5/5 | 100 | |
Lung-to-Lung | 4 | 5/5 | 0/5 | 5/5 | 100 |
5 | 5/5 | 1/5 | 4/5 | 100 | |
6 | 5/5 | 0/5 | 5/5 | 100 | |
7 | 5/5 | 1/5 | 4/5 | 100 | |
8 | 5/5 | 1/5 | 4/5 | 100 | |
9 | 7/7 | 7/7 | 0/7 | 100 | |
10 | 7/7 | 6/7 | 1/7 | 100 | |
11 | 7/7 | 6/7 | 1/7 | 100 | |
12 | 7/7 | 0/7 | 7/7 | 100 | |
13 | 7/7 | 3/7 | 4/7 | 100 |
DBA/1J mice were inoculated with 1.4 × 106 PFU SW293 or 50 μL lung homogenate obtained from infected mice. Mortality rates were observed for nine days