FIG 2.

Configurations of Mga regulons. In the large collection of contiguous Mga regulon sequences, we identified 10 possible configurations of the regulon based on presence and positions of genes. All Mga regulons began and ended with the mga and scpA genes and could contain genes for Mrp, Emm, Enn, Pgs, protein H, SIC, and transposases. The most frequent Mga regulon configuration, with genes for the trio of M and M-like proteins, was present in around 74% of genomes, from emm types that are responsible for around half of global infections.