Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition constant Ki values for purified BLIPK74T/W112D variant against several β-lactamases
| β-Lactamase | Ki (nM) |
|---|---|
| KPC-2 | 2.4 ± 0.4 |
| KPC-3 | 2.5 ± 0.4 |
| KPC-4 | 1.2 ± 0.2 |
| KPC-5 | 1.5 ± 0.3 |
| KPC-6 | 1.3 ± 0.3 |
| KPC-7 | 1.5 ± 0.3 |
| KPC-8 | 1.6 ± 0.3 |
| KPC-9 | 0.7 ± 0.1 |
| CTX-M-14 | 908 ± 24 |
| CTX-M-15 | 433 ± 87 |
| TEM-1 | 6,240 ± 1,112 |
| NDM-1 | NMa |
| OXA-48 | 1,181 ± 129 |
NM, no measurable inhibition.
