Table 2.
Categories of Initial PPI Indication and Long-Term Indication Stratified by Appropriateness
| Potentially Low- Value (n=143) n (%) |
Appropriate (n=254) n (%) |
Total (N=399) n (%) |
|
|---|---|---|---|
| Categories of Initial Indication for PPI (%) | |||
| GERD | 95 (66.4) | 163 (64.2) | 258 (65.0) |
| Peptic ulcer disease | 5 (3.5) | 15 (5.9) | 20 (5.0) |
| Chronic cough | 5 (3.5) | 4 (1.6) | 9 (2.3) |
| Atypical GERD symptoms | 4 (2.8) | 7 (2.8) | 11 (2.8) |
| Dyspepsia | 4 (2.8) | 7 (2.8) | 11 (2.8) |
| Laryngopharyngeal reflux | 3 (2.1) | 3 (1.2) | 6 (1.5) |
| Suspected Upper GI bleed | 3 (2.1) | 2 (0.8) | 5 (1.3) |
| Ulcer bleeding prophylaxis | 3 (2.1) | 5 (2.0) | 8 (2.0) |
| H. pylori eradication | 1 (0.7) | 1 (0.4) | 2 (0.5) |
| Unable to determine | 14 (9.8) | 14 (5.5) | 28 (7.1) |
| Anticoagulation | 0 (0.0) | 1 (0.4) | 1 (0.3) |
| Other | 6 (4.2) | 32 (12.6) | 38 (9.6) |
| Categories of Potentially Low-Value PPI (%) | |||
| Use extended long-term for a short-term indication | 116 (81.1) | NA | 116 (81.1) |
| No identifiable indication for use | 18 (12.6) | NA | 18 (12.6) |
| Use for indication not recommended by guidelines | 6 (4.2) | NA | 6 (4.2) |
| Started inpatient and continued to outpatient without indication | 1 (4.2) | NA | 1 (4.2) |
| Other | 1 (0.7) | NA | 1 (0.7) |
| Unknown | 1 (0.7) | NA | 1 (0.7) |
PPI = Proton Pump Inhibitor; GI = Gastrointestinal; GERD = Gastroesophageal Reflux Disease