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. 2020 Jan 7;26(1):21–34. doi: 10.3748/wjg.v26.i1.21

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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The association between phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 expression and clinical features. A: The expression of phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1) in blood samples of gastric cancer patients, normal gastric tissues, and gastric tumor tissues; B: The expression of PREX1 was examined in gastric cancer patients with the different patient stage; C: The level of PREX1 was assessed in gastric cancer patients with different tumor grade; D: The level of PREX1 was examined in those gastric cancer patients with lymph node metastasis or not. Statistical significance is expressed as ^aP < 0.05, ^bP < 0.01, ^eP < 0.001. TPM: Transcript per million; PREX1: Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1; TCGA: The Cancer Genome Atlas.