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. 2020 Jan 7;26(1):21–34. doi: 10.3748/wjg.v26.i1.21

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 was closely associated with the regulation of cell adhesion. A: The Gene Set Enrichment Analysis analysis of phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1) and co-expression network in gastric cancer; B: The correlation between PREX1 and transforming growth factor β1 were conducted in gastric cancer; C: The correlation between PREX1 and transforming growth factor β2 were conducted in gastric cancer; D: The correlation between PREX1 and intercellular adhesion molecule-1 were conducted in gastric cancer; E: The correlation between PREX1 and integrin alpha 4 were conducted in gastric cancer; F: The correlation between PREX1 and integrin alpha 5 were conducted in gastric cancer. TPM: Transcript per million; FDR: False discovery rate; NES: Normalized enrichment score; TGFβ1: Transforming growth factor β1; TGFβ2: Transforming growth factor β2; ICAM1: Intercellular adhesion molecule-1; ITGA4: Integrin alpha 4; ITGA5: Integrin alpha 5; PREX1: Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1.